Not everyone can see, hear, move or process information easily if at all. They may have sensory, physical, or cognitive impairments that limit their ability to perform one or more activities.
253 million people are visually impaired, due to disease, trauma or degenerative conditions, 1 in 7 people suffer from a mobility issue, over 1.5 billion people have some sort of hearing loss, while over 70 million people suffer from epilepsy, vestibular disorders or have a speech impediment.
We generally refer to them as people with disabilities. While some people are born with a disability, others may have acquired one due to an event like a sports injury, onset health condition or even old age. Some disabilities can be temporary (e.g. broken arm and cannot use a mouse) or even situational (e.g. in a crowded subway and cannot hear the conversation in a video).
According to the Social Model, a disability is something we experience, a disadvantage caused by society. Contrast that to an impairment, which is a description of the physical body.